Overview of NanoDisk technology
Cancer Therapies
- Ghosh, M. and Ryan, R.O. (2014) ApoE enhances nanodisk-mediated delivery of curcumin to glioblastoma multiforme cells. Nanomedicine (London). 9, 763-771.
- Ghosh, M. and Ryan, R.O. (2014) Curcumin homing to the nucleolus: mechanism for initiation of an apoptotic program. J. Nutr. Biochem. August 4, Epub ahead of print.
- Singh, A.T., Ghosh, M., Forte, T.M., Ryan, R.O., and Gordon, L.I. (2011) Curcumin nanodisk-induced apoptosis in mantle cell lymphoma. Leukemia & Lymphoma. 52, 1537-153.
- Tadmor, T. and Polliack, A. (2011) Mantle cell lymphoma: curcumin nanodisks and possible new concepts on drug delivery for an incurable lymphoma. Leukemia & Lymphoma. 52: 1418-1420.
- Ghosh, M., Singh, A.T.K., Sulchek, T., Gordon, L.I. and Ryan, R.O. (2011) Curcumin nanodisks: formulation and characterization. Nanomedicine. 7, 162-167.
- Singh A.T., Evens A.M., Anderson R.J., Beckstead J.A., Sankar N., Sassano A., Bhalla S., Yang S., Platanias L.C., Forte T.M., Ryan R.O. and Gordon L.I. (2010) All trans retinoic acid nanodisks enhance retinoic acid receptor mediated apoptosis and cell cycle arrest in mantle cell lymphoma. Br. J. Haematol. 150, 158-69.
- Iovannisci, D.M., Beckstead, J.A. and Ryan, R.O. (2009) Targeting nanodisks via a single chain variable antibody - apolipoprotein chimera. Biochem. Biophys. Res. Commun. 379, 466-469.
- Redmond, K.A., Nguyen, T.-S. and Ryan, R.O. (2007) All-trans retinoic acid nanodisks. Int. J. Pharm. 339, 246-250.
Infectious Diseases
- Cole, P.A., Bishop, J.V., Beckstead, J.A., Titus, R and Ryan, R.O. (2014) Effect of amphotericin B nanodisks on Leishmania major infected mice. Pharmaceutica Analytica Acta. 5, 8.
- Burgess, B.L., He Y., Luo B., Ryan R.O., Carroll S.F., Forte T.M., Oda M.N. (2012) NanoDisk-Amphotericin B is Superior to Liposomal Amphotericin B in Murine Models of Pulmonary and Disseminated Aspergillosis. ICAAC 2012 Poster.
- Burgess, B.L., Cavigiolio G., Fannucchi M.V., Illek B., Forte, T.M., Oda, M.N. (2010) A phospholipid-apolipoprotein A-I nanoparticle containing amphotericin B as a drug delivery platform with cell membrane protective properties. Int J Pharm. 399 (1-2): 148-55.
- Tufteland, M., Selitrennikoff, C.P. and Ryan, R.O. (2009) Nanodisks protect amphotericin B from ultraviolet light and oxidation induced damage. Pest Manag. Sci. 65, 624-628.
- Nguyen, T.-S., Weers, P.M.M., Raussens, V., Wang, Z., Ren, G., Sulchek, T, Hoeprich, P.D. Jr. and Ryan, R.O. (2008) Amphotericin B induces interdigitation of apolipoprotein stabilized nanodisk bilayers. Biochim. Biophys. Acta. 1778, 303-312.
- Tufteland, M., Pesavento, J.B., Bermingham, R.L., Hoeprich, P.D., Jr., and Ryan, R.O. (2007). Peptide stabilized amphotericin B nanodisks. Peptides. 28, 741-746.
- Nelson, K.G., Bishop, J., Ryan, R.O. and Titus, R. (2006). Nanodisk-associated amphotericin B clears Leishmania major cutaneous infection in susceptible BALB/c mice. Antimicrob. Agents Chemother. 50, 1238-1244.
- Hargreaves, P.L., Nguyen, T-S. and Ryan, R.O. (2006) Spectroscopic studies of amphotericin B solubilized in nanoscale bilayer membranes. Biochim. Biophys. Acta. 1758, 38-44.
- Oda, M.N., Hargreaves, P.L., Beckstead, J.A., Redmond, K.A., Van Antwerpen, R., and Ryan, R.O. (2006). Reconstituted high density lipoprotein enriched with the polyene antibiotic amphotericin B. J Lipid Res. 47, 260-267
Neurodegenerative Diseases